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What adjuvant treatment would you use for a cisplatin ineligible, node positive, upper tract urothelial cancer patient after radical nephroureterectomy?

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What are the adjuvant treatment options for N+ upper tract urothelial cancers post RNU who is cisplatin ineligible?

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1 Answer
Mednet Member
Mednet Member
Medical Oncology · Hematology-Oncology Associates of Fredericksburg, Inc.
Answered on · Updated on

Based on the recent POUT trial, there is no benefit in substituting cisplatin with carboplatin. In fact, node positive patients tended to do worse even with chemotherapy. I routinely consider adjuvant IO trials for these patients like AMBASSADOR. If patient is not able to participate in trials, it m...

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