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Topics:
Psychiatry • General Outpatient Psychiatry • Ketamine • Depression • Major Depressive Disorder
What antidepressant medications do you usually use alongside ketamine or esketamine treatment in patients with difficult-to-treat depression?
In your clinical practice, have you noticed whether concurrent pharmacotherapy improves the durability of ketamine’s effects? Which medications do you find most effective?
Answer from: at Community Practice
Truly, I have not appreciated significant differences among concurrent medications. I believe there have been some theoretical concerns about antidepressants and other psychiatric medications that should not be used along with ketamine, but I don’t believe these concerns panned out in clinical...
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Answer from: at Academic Institution
Hello--ketamine clinic psych here. In our clinic's experience, quite a few ketamine-responders can drop the number of medications or lower the doses of medications once ketamine is part of the treatment plan. We don't see a lot of difference between which medication works best since that is so varia...