What approach is suggested for extended adjuvant endocrine therapy in a HR+ breast cancer?  

The goal of extended adjuvant endocrine therapy, which is treatment beyond the initial five years, is to reduce the risk of a late cancer recurrence. The decision is highly personalized and based on balancing this potential benefit against side effects and a patient's quality of life. The most impo...

Just a few additional comments: First, for premenopausal women who have completed 5 years of tamoxifen, if the risk of recurrence is sufficiently high to justify extended adjuvant therapy, ovarian function suppression and AI should be considered in place of an additional 5 years of tamoxifen. Secon...