What are outpatient strategies to mitigate taxane-induced peripheral neuropathy?

Topics: Medical Oncology • Supportive Care • Neuropathy • Neurology

Are there any protocols in place? Aside from telling patients to use ice packs or bags or immerse hands/feet in ice water baths from 15" before to 15" after chemotherapy, are there any other cooling devices on the market that anyone would recommend? Is anyone routinely recommending this for patients at high risk of chemo induced sensory neuropathy due to pre diabetes/diabetes/underlying neuropathy?

Answer from: Medical Oncologist at Community Practice

At the present time, there are no established means for preventing taxane-induced neuropathy other than limiting the dose that is given. In patients who are receiving taxane therapy and have developed significant neuropathy, ASCO guidelines suggest that discussion should be had with patients with re...

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Medical Oncologist at Breastlink Medical Group
I allow myself to be less evidence based and more ...

Answer from: Medical Oncologist at Academic Institution

It is interesting that randomized trials have not shown an improvement in neuropathy using cryotherapy. We use docetaxel most commonly in the breast and prostate population. Since instituting cryotherapy approximately two years ago, the incidence of neuropathy and nail changes has dramatically decre...

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Medical Oncologist at SBLHS
Thanks. Can you explain this more in detail? How d...

Medical Oncologist at Colorado Permanente Medical Group Hematology & Oncology
Thanks to all for the helpful comments. It's good ...

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