Topics:
Health Disparities • Rheumatology • Systemic lupus erythematosus • Pediatric Rheumatology • ACR Journal Club
What are some explanations for the persistent renal outcome disparity gaps affecting certain minority groups of patients with pediatric SLE despite improvement in overall renal outcomes?
What would you suggest to help address these disparities in our own practices?
Answer from: at Academic Institution
There are likely some genetic causes, for example, Blazer et al., PMID 33461980 have shown in a Ghanian cohort of patients with SLE that apolipoprotein 1 risk variants are associated with progressive renal failure. However, it is undeniable that in the US, children in minoritized groups are dispropo...
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Answer from: at Academic Institution
While it wasn’t possible for us to determine this from our data, I think it’s important to keep in mind that treatment paradigms or healthcare practices that benefit a population on average do not necessarily address the root causes of disparities. As an example, if residential neighborh...