What are treatment options for a pediatric patient with PRETEXT IV hepatocellular carcinoma with progressive disease following PLADO and sorafenib and 3 sessions of TACE?
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What would be your preferred treatment regimen for a pediatric patient with PRETEXT IV HCC with progressive disease following PLADO, sorafenib, and TACE?
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2 Answers
Mednet MemberInvited Expert
Pediatric Hematology/Oncology · FibroFighters Foundation
Answered on
Does this patient definitely have HCC? Or could it be fibrolamellar carcinoma - specifically, did she/he have the DNAJB1-PRKACA fusion?
I can help with FLC for sure. I have seen over 250 FLC patients.
For HCC, I have only seen about 10, though some do respond to "FLC-like" therapy, such as GEMOX-LEN...
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Mednet MemberInvited Expert
Pediatric Hematology/Oncology · FibroFighters Foundation
Answered on
What happened with this patient?
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