What are your indications for radiotherapy in children with pleomorphic xanthoastrocytoma?
Would you manage this histology any differently relative to other low grade gliomas? Is a STR a definite indication for postoperative XRT?
1 Answer
Mednet Member
Radiation Oncology · St Jude Children's Research Hospital
Answered on
Pleomorphic Xanthoastrocytoma is unique among other pediatric low grade gliomas in that it there is a high frequency of targetable alterations including BRAF V600E alterations and that there appears to be an increased risk of transformation relative to other pediatric low grade glioma histologies (P...
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