What are your preferred lipid-lowering agents and target LDL reduction goal following initiation of therapy for patients with familial hyperlipidemia without underlying CAD? 

It is not easy to address this question without specifics of the 'familial hyperlipidemia," but I will give examples:

1. Monogenic familial hypercholesterolemia - since the LDL is very high from early childhood, we tend to treat adolescents with statins with a goal of a 50% reduction (20 or 40 rosuvas...

I agree with Dr @Henry Ginsberg that familial hyperlipidemia is a term that is difficult to interpret without the actual lipid panel and family history data.

If the genetic condition is a primary severe hypercholesterolemia (monogenic FH or polygenic hypercholesterolemia), statins and nonstatins bas...