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What are your top takeaways from AHA 2025?

1 Answer
Mednet MemberInvited Expert
Cardiology · Icahn School of Medicine at Mount Sinai
Answered on
  • The signal across fields: cardiology is moving toward biology + behavior to prevent and treat disease earlier/better.
  • POLY-HF: A single once-daily polypill (β-blocker + MRA + SGLT2i) in HFrEF improved LVEF, QOL, and cut HF events by ~60% vs usual care → major signal that adherence-first strategies can move outcomes in underserved communities.
  • FOOD-HF: Medically tailored meals and produce boxes improved HF quality of life, even without changing readmissions → “food-as-medicine” is now a serious HF intervention.
  • DECAF: patients who drank ≥1 cup of caffeinated coffee daily after cardioversion had significantly fewer AF recurrences (47% vs 64%), suggesting that moderate coffee intake is not only safe but may be protective in AF.

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