What are your top takeaways in GI Cancers from ESMO 2025?  

The new results from CheckMate 8HW confirmed an ORR of 73% vs 61%, with a “not reached” median duration of response. Importantly, I note that the time to response is 2.8 months. The confirmed and updated PFS at 4 years is 64% vs 49%. The OS at 4 years is 78% vs 65%. BREAKWATER at ASCO 20...