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What are your top takeaways in Hematologic Malignancies from ASCO 2024?

5 Answers
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Medical Oncology · Mayo Clinic
Answered on

The top three would be

  1. IMROZ
  2. DREAMM-8
  3. BENEFIT

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Medical Oncology · Dana-Farber Cancer Institute
Answered on

I would say I’m a DREAMMer :)
The DREAMM-8 (BPd vs PVd) results were truly impressive.

Both DREAMM-7 and DREAMM-8 trials illustrate how well Belantamab Mafodotin pairs with proteasome inhibitors and immunomodulatory agents. In addition, for patients with relapsed refractory myeloma, having been lenali...

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Hematology · The Ohio State University - James Cancer Hospital and Solove Research Institute
Answered on

Always an exciting conference for myeloma and this year was no exception.

1. IMROZ study: The management of newly diagnosed multiple myeloma (NDMM) has evolved significantly over the past few years. One of the first clinical assessments in planning treatment is determining eligibility for autologous ...

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Medical Oncology · Washington University School of Medicine
Answered on
The DREAMM-7 and DREAMM-8: Impressive results in terms of PFS. Will likely lead to the reintroduction of belantamab into clinical practice and offer another potential BCMA-based therapy amenable to administration in the community setting.
IMROZ: Will lead to the ability to give “Isatuximab based qua...

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Medical Oncology · University of Washington, Fred Hutchinson Cancer Research Center
Answered on

For multiple myeloma, my "top 3" presentations were:

  1. BENEFIT/IFM 2020-05 study (Leleu et al., #7501) - Isa-VRd with once-weekly bortezomib beat Isa-Rd in transplant-ineligible patients with regard to MRD negativity (PFS results still pending). This study is getting overshadowed by IMROZ, which is un...

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