What biologic for psoriasis do you prescribe most often in patients with a history of malignancy?
Answer from: at Academic Institution
I like an IL-17 inhibitor for psoriasis with a current or history of malignancy. IL-17 is involved with cancer neoangiogenesis, so blocking it may have an anti-tumor effect. This hasn’t been studied yet but it makes me feel better that the IL-17 class doesn’t have an increased risk of ca...
Comments
at Forefront Dermatology Interesting point because the same exact thing has...
at LindaSusan Marcus, MD IL 23 has no black box warning and works nicely so...
I think this needs to be done as part of shared decision-making. I am generally comfortable with all biologics in those with solid organ malignancy. I prefer IL23s in those with lymphoma because IL23s can induce remission. So I will give the loading dose and then dose the patient on demand. I always...
Interesting point because the same exact thing has...
IL 23 has no black box warning and works nicely so...