Topics:
Radiation Oncology • Genitourinary Cancers
What bowel dose constraints do you use when treating bladder cancer with moderate hypofractionation?
Using the standard whole bladder dose fractionation used in BC2001, 55 Gy in 2.75 Gy fractions.
Answer from: Radiation Oncologist at Community Practice
Two additional steps I take when using hypofractionation doses as noted above is to 1) ensure that the V55 Gy to small bowel is limited to less than 5 cc (based on some data in gynecological cancers) and 2) make sure the full thickness bowel loop is not in the PTV2 volume.
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Answer from: Radiation Oncologist at Community Practice
Good question. In the BC2001 trial reduced high-dose volume (RHDV) arm, PTV1 was outer bladder wall + 1.5 cm and PTV2 was the bladder tumor + 1.5 cm. Oncologic results were similar with RHDV treatment compared to whole bladder irradiation. The hypofractionation option prescription for PTV2 was 55 Gy...
Comments
Radiation Oncologist at City of Hope
I am curious about the empty bladder part. I wou...
I am curious about the empty bladder part. I wou...
Radiation Oncologist at The Oregon Clinic-Radiation Oncology West
When treating whole bladder then boost (as opposed...
When treating whole bladder then boost (as opposed...