What brachial plexus dose constraints do you apply when treating conventionally fractionated NSCLC?
Yes. I am presuming you are discussing treating definitively with CRT for locally advanced NSCLC.
Since RTOG 0617, most people that treat NSCLC prescribe to a dose of 60-66 Gy in 30-33 fx, as this is a feared toxicity that is very painful and decreases QOL. We try to keep the brachial plexus dose to ...
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Agreed with Dr. @Dr. First Last. Of note, if you are treating a superior sulcus tumor near the brachial plexus, you might consider the Intergroup 0160 regimen of pre-op chemoRT followed by surgery. In this trial, they used a dose of 45 Gy/25# with cisplatin/etoposide, but one could go higher to a de...
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NCCN lists median brachial plexus dose constraint as < 69Gy for conventionally fractionated 30-35Fx regimen. (When I inquired a while back, they confirmed this wasn't a typo).
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