What class(es) of antihypertensives should be considered next for refractory hypertension in a patient compliant with high doses of Entresto, chlorthalidone, amlodipine, clonidine, and spironolactone if they previously did not have any improvement on beta blocker or hydralazine and work-up for secondary causes were unremarkable?

At what point should we consider referral for renal denervation therapy?

Answer from: at Community Practice

Minoxidil remains a rarely used but potent option.

Comments

at The George Washington University Hospital
Alpha blockade is often forgotten. Upward titrated...

at Heart And Vascular Center Of Arizona
Agree with the alpha blocker. Renal denervation, I...

Answer from: at Community Practice

I think it is reasonable at this point to refer the patient for renal denervation. Current data support improvement of the patient’s blood pressure control to somewhat of a more acceptable degree.

Answer from: at Academic Institution

Lisinopril, denervation...

Comments

at Valley Presbyterian Hospital
Patient is on Entresto. Lisinopril would be contra...

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