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What class(es) of antihypertensives should be considered next for refractory hypertension in a patient compliant with high doses of Entresto, chlorthalidone, amlodipine, clonidine, and spironolactone if they previously did not have any improvement on beta blocker or hydralazine and work-up for secondary causes were unremarkable?

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3 Answers
Mednet Member
Mednet Member
Cardiology · Endeavor Health

Minoxidil remains a rarely used but potent option.

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Cardiology · NYU Langone - New York

I think it is reasonable at this point to refer the patient for renal denervation. Current data support improvement of the patient’s blood pressure control to somewhat of a more acceptable degree.

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Cardiology · Fountain Valley Regional Hospital and Medical Center

Lisinopril, denervation...

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