What considerations guide your decision to perform endovascular therapy in stroke involving acute M2 or M3 occlusions?

When deciding whether to intervene in distal occlusions, I first assess the severity of the neurological deficits, particularly focusing on cortical signs such as aphasia, neglect, or visual field deficits. Based on criteria from prior LVO RCTs, I typically use an NIHSS threshold of 6 or greater...