What do you recommend as a first-line antidepressant in patients with major depressive disorder and migraines?
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2 Answers
Mednet Member
Neurology · Kaiser Permanente Fremont Medical Center
In my clinical practice, I have found SNRI medication, particularly extended-release venlafaxine (dosed from 37.5 mg to 225 mg), to be helpful for patients with both comorbidities. Other medication classes I have seen used to good effect include TCAs (amitriptyline, nortriptyline) and some SSRIs (se...