What do you use to treat a kidney transplant patient with progressive BK nephropathy despite a maximal decrease in immunosuppression for months?
1 Answers
Mednet Member
Nephrology · Dell Medical School
Assuming you are referring to actual BK nephropathy (biopsy evidence of viral inclusion on renal tubular cells staining positive by SV40 either by IF or immunohistochemistry) + serum BK viral PCR.
Beyond lowering immunosuppression, adjunctive therapy (none of which are FDA approved of course) includ...