What dose and fractionation do you use to palliate mycosis fungoides lesions?

Topics: Hematologic Malignancies • Radiation Oncology • Hematology

There seems to be a wide variety of palliative doses used in clinical practice (8 Gy x 1, 2 Gy x2, and 20 Gy in 10 fx). Do you have a preferred dose? Do you think 2 Gy x 2 is enough of a palliative dose for mycosis?

Answer from: Radiation Oncologist at Academic Institution

I will admit that I utilize a wide range of fractionation schedules, depending on the clinical circumstances, when treating mycosis fungoides. The data suggests that 2 Gy X 2 is not an effective palliative schedule, with a CR rate of only ~30% with almost all lesions requiring re-treatment (IJROBP 2...

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Radiation Oncologist at Munson Medical Center
Do you change your dose/fractionation regimen for ...

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