Topics:
Radiation Oncology • Gastrointestinal Cancers
What dose constraints do you use for 15-25 fraction hypofractionated RT for cholangiocarcinoma?
Higher radiation dose was shown to be associated with longer survival in Tao et al., JCO 2016. What dose constraints do you use when using these regimens?
Answer from: Radiation Oncologist at Academic Institution
For the GI tract, we use point dose constraints and 40cc “guidelines” that are based on our publications in LAPC and IHCC, where we analyzed bleeding events and found that is has been related to 40cc getting more than 50Gy in 25. So, we use 40cc over 45Gy in 25fx and 37.5Gy in 15fx. Blee...
Do you use any specific dose/volume parameters on ...