What dose do you use to palliate multiple myeloma in a vertebral body?
Does your dose recommendation change if a patient has cord compression or has undergone surgery? There is a range of doses in the ILROG guidelines, including 8Gy x1, 20Gy in 5, 30Gy in 10 and 24Gy in 12.
Answer from: Radiation Oncologist at Community Practice
For ISS Stage 1 MM patients who are going to have an OS of over 10 years, I generally prefer a more protracted regimen of 25 Gy in 10 fractions for improved durability of pain control. I typically only treat the symptomatic VB only and use inverse planning. If there is gross epidur...
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Answer from: Radiation Oncologist at Academic Institution
We generally do 30/10, especially if there is evidence for cord compression or patient underwent surgery. If patient has a poorer prognosis or is about to transfer to hospice in this situation then we'll more strongly consider 20/5 or 8Gy x 1, respectively. There is no wrong answer here (IMO) and it...
Answer from: Radiation Oncologist at Community Practice
For the palliative treatment of bone only disease with no cord compression I use 8 Gy in 1 fraction. It’s interesting that despite multiple trials for bone mets showing single fraction RT is as good as multifraction RT, it is still an underused fractionation scheme. At ASTRO this year, single ...
Answer from: Radiation Oncologist at Academic Institution
15 Gy in 5 fractions.
Answer from: Radiation Oncologist at Community Practice
20 Gy / 8 fx is an MDACC dose. Some thought of reduced marrow toxicity with lower dosage, plus it is a very responsive histology.
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Radiation Oncologist at Providence St Mary Cancer Center
Do you try to further reduce marrow toxicity when ...
Do you try to further reduce marrow toxicity when ...