Topics:
Hematologic Malignancies • Radiation Oncology
What dose-fractionation scheme do you recommend for the treatment of leukemia cutis?
Does your recommendation change based on whether the patient has one or multiple lesions?
Answer from: Radiation Oncologist at Community Practice
Leukemia cutis (LC) is a form of cutaneous extra-medullary leukemia that confers a relatively poor prognosis, with a median survival of <12 months. Since most of these patients have additional sites of involvement (spleen, liver, CNS), the mainstay of treatment of EMD leukemias is still considere...
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Answer from: Radiation Oncologist at Community Practice
Really thorough answer above. I recently had a case - young guy with AML, with clear marrow but progression in the skin. I consulted with multiple experts in our field at MDACC and KU - was going to do 20 Gy over 5 weeks, which was pretty consistent amongst those I asked. Was going to boost sites of...