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What dose/fractionation scheme would you employ to palliate a metastatic colon cancer patient with several large painful anterior abdominal wall lesions?

The patient had previously recurred twice in the abdominal wall, and was treated with resection. The patient has developed AML since that time and is no longer a candidate for chemotherapy.
1 Answer
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Radiation Oncology · Memorial Sloan-Kettering Cancer Center
Answered on · Updated on

Due to the prior surgery, there is almost always fixed bowel adherent to these scar/peritoneal recurrences. That is almost always the dose limiting OAR. The fractionation depends on the PS and life expectancy. From the description, the prognosis sounds poor so 20 Gy in 5, 30 Gy in 10, or 35 Gy in 14...

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