Topics:
Radiation Oncology • Gastrointestinal Cancers
What dose should you treat the anal canal after excision of a T1 anal cancer with positive margins?
Is it still necessary to treat to 50 Gy or can a lower dose safely be used as there is no gross disease (e.g., 42 Gy in 28 fractions to nodes and the anal canal)?
Answer from: Radiation Oncologist at Academic Institution
I would, under no circumstance, treat this patient to a dose of 50 Gy. For a T1 tumor (even unresected) that is likely an excessive dose. Keep in mind that the initial reports of RT and chemo used a dose of about 30 Gy with complete pathological response. There are data to suggest that doses of abou...
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