I most commonly prescribe 50-100mg daily, but I may titrate up to 150mg occasionally as needed. I prefer QAM dosing to minimize diuresis in the evening. I find that starting at 25mg and up-titrating by 25mg weekly leads to better tolerability, especially when it comes to orthostasis and dizziness.&n...

First of all, remember that all acne is hormonal, and probably just about any woman with acne can benefit from spironolactone. My dosage range is 25mg-100mg per day, either QD or divided BID (for the higher doses). I have preferred to start low and pull the dose up after a few weeks. We do know that...