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What drives you to choose voclospsorin over tacrolimus given the substantially higher cost?

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Which of these factors most heavily weighs in your decision to choose voclosporin over tacrolimus for patients with lupus nephritis?

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2 Answers
Mednet Member
Mednet MemberInvited Expert
Rheumatology · NYU Langone Health
Answered on · Updated on

In a discussion of comparing voclosporin versus tacrolimus to treat LN, I would first like to address the issue of cost. As far as any individual patient, out-of-pocket expenses may be similar for these two calcineurin inhibitors since it is often covered by insurance. Additionally, Aurinia has a ve...

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Mednet Member
Mednet Member
Nephrology · Columbia University
Answered on

Choosing voclosporin over tacrolimus for lupus nephritis involves weighing various factors beyond cost. Here are some key considerations:

  1. Efficacy
    • Voclosporin: Clinical trials, such as the AURORA 1 and AURORA 2 studies, have demonstrated that voclosporin, in combination with mycophenolate mofeti...

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