What factors do you consider when deciding to treat IgA nephropathy with immunosuppression in a patient with cirrhosis, given the possibility that IgA nephropathy could be secondary to cirrhosis?  

Proteinuria is the most important factor here. If there is significant proteinuria (>1 g/d) and no other clear reason for it, I would treat the IgA nephropathy with immunosuppression. Secondary IgA due to cirrhosis is usually not associated with significant proteinuria.

This would constitute a secondary form of IgA Nephropathy and immunosuppression is not generally not given. Treatment of secondary forms of IgA Nephropathy mandates treatment of the underlying etiology.