What factors do you weigh most heavily in the selection of radiotherapy versus topical treatments for lentigo maligna in a patient who is not a surgical candidate?   

The ability of a patient to travel to multiple sessions of radiotherapy would play a major role in making this decision. If the patient is frail and has someone who could reliably to topical therapy, it might make me lean towards topical therapy.

I agree completely with Dr. @Arbiser that frailty is one of the most important criteria for selecting radiation for any type of skin cancer. In Europe, frailty is considered a medical condition. I also agree that the ability to have multiple treatments, and in the case of electron beam, to be immobi...