What first line treatment would you consider for a patient with stage IV gastric cancer that is HER2 negative and MSI-high?
Answer from: Medical Oncologist at Community Practice
For a patient with MSI-H, HER2 negative metastatic gastric cancer, PD1 blockade with pembrolizumab (pembro) would be my first choice. The KEYNOTE-062 data support the efficacy of pembro in this setting [Shitara et al., PMID 32880601].The phase 3 KEYNOTE-062 study randomized patients with untreated, ...
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Would you use IO monotherpy or IO-chemo? The respo...
Nivolumab and Chemotherapy if CPS is more than 5. ...
Joseph Chao et al., PMID 33792646 did a post hoc a...