What fractionation would you offer to a young pre-menopausal woman with early stage ER+/HER2- breast cancer who received adjuvant chemotherapy and is highly interested in maximizing breast cosmesis?
Assume no contraindications to hypofractionation.
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What whole breast fractionation would you use?
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2 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
40 Gy in 15 fractions with focus on dose homogeneity aiming for V105 < 5%.
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Radiation Oncology · Vanderbilt-Ingram Cancer Center
Answered on
The 2011 WBI guidelines had a lack of consensus of the best hypoFX regimen in the chemotherapy era given a paucity of research on the safety of the hypoFX regimen back when those guidelines were created.
Moderate hypofractionation (with or without a boost) has better cosmetic outcomes in START A/B (H...
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