What further evaluation do you pursue for patients who present with vague symptoms such as subjective fevers or intermittent night sweats, who have no pulmonary symptoms but have a positive IGRA?

What further evaluation do you pursue, besides obtaining a chest X-ray, for patients who present with vague symptoms such as subjective fevers or intermittent night sweats, who have no pulmonary symptoms but have a positive IGRA?

• Ask about weight loss and compare weights with past visits
• Inquire about any localizing symptoms (e.g., hip pain, back pain, hematuria)
• Proceed with additional imaging (e.g., CT scan) if CXR is normal and there are no weight loss or localizing symptoms
• Initiate treatment for latent TB infection (LTBI) if no further significant symptoms are present
• Other