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What high dose rectal constraints do you use when using a hypofractionated prostate regimen?

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Mednet Member
Mednet Member
Radiation Oncology · Duke University School of Medicine

Of course the answer is different depending on which hypofractionated regimen that you use.

If you are using the CHHiP regimen (60 Gy in 20 fractions) the trial investigators have updated their recommended constraints based on the observed toxicities in the trial.

In a preproof online they have provid...

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Mednet Member
Mednet Member
Radiation Oncology · University of Chicago

When we switched towards hypofractionation for intact prostate cancer (going from 39 fx to 20 fx) we adopted a pragmatic approach towards dose constraints. Our constraints for a 78 Gy prescription [e.g. rectal V70, V65, V40 Gy get <10%, 20%, and 40%] were proportionally matched to a 60 Gy prescripti...

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