What high risk features for stage IB NSCLC would lead you to consider adjuvant chemotherapy?
Do you consider size > 2cm, visceral pleural invasion or vascular invasion as indications for cisplatin-based chemotherapy?
2 Answers
Mednet MemberInvited Expert
Medical Oncology · University of Michigan Medical School
Answered on
Short answer is "no", I would not change practice based on the recently presented (ASCO) a non-randomized analysis of the potential benefits of adjuvant chemotherapy for patients with stage I NSCLC in Japan (Tsutani, et al. JCO 37(15S):457s, 2019; abst 8500). Many of these patients received UFT rath...
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Mednet MemberInvited Expert
Medical Oncology · Indiana University
Answered on
High risk features in stage IB NSCLC would include presence of lymphovascular invasion, poor differentiation, or high standardized uptake value (SUV) on positron emission tomography (PET; variably defined as SUV 10 or more. I don't think size of 2cm has been an accepted high risk features. Tumor siz...
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