What, if any, role does systemic therapy have in the treatment of HCC amenable to definitive locoregional therapy?
Answer from: Medical Oncologist at Academic Institution
For ablation, TACE and Y90, I traditionally hold back on systemic therapy so that I have something I can use if they develop metastases. Also, sorafenib has been not shown to be effective in the adjuvant setting so I apply that principle here. Bruix et al., PMID 26361969
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