What is the appropriate amount of time to allow for wound healing prior to post-operative radiation for metastatic disease?

I typically have waited about 4 weeks or so to start RT after ORIF. In addition to limiting risk of wound complications, this allows time for the patient to adequately recover from a pain perspective, since if one tries to treat earlier, the tolerance of treatment is often poorer.

In situations where the goal is to start systemic therapy ASAP if there are multiple other sites of metastatic disease and if the patient can tolerate it, I have delivered PORT as early as 2 weeks after ORIF if also felt to be acceptable from the surgeons' perspective and if the patient has recovered well/can tolerate it.