What is the appropriate dose to the dissected node-negative neck with indication for radiation due to advanced primary?   

Is it 54 Gy or do we worry about hypoxia and need to go to 60 Gy? Does it change based on site (i.e., oral cavity versus a T4N0 larynx)?

There appears to be a range between 50-60 Gy based on previous discussions, examples below:

https://www.themednet.org/question/1465

https://www.themednet.org/question/882

https://www.themednet.org/question/9454

https://www.themednet.org/question/12384



Answer from: Radiation Oncologist at Academic Institution
Comments
Radiation Oncologist at Kansas City VA Medical Center
50 Gy/25 fractions are supposed to eradicate over ...
Radiation Oncologist at University of Florida
50 Gy/25 fractions per Gilbert Fletcher is for und...
Radiation Oncologist at Swedish Covenant Hospital (Chicago IL)
True but at the same time, the risk of failure in ...
Radiation Oncologist at Washington University School of Medicine
Yes, at WashU, we have data from a phase II trial ...
Radiation Oncologist at Atlanta Oncology Associates
In what scenario would you radiate a pN0 dissected...
Radiation Oncologist at University of Texas MD Anderson Cancer Center
One has to be very careful regarding the "phase 2 ...
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Answer from: Radiation Oncologist at Academic Institution