Mednet Logo
HomeQuestion

What is the appropriate interval to obtain a hydroxychloroquine level after making a dosage adjustment?

1
1 Answers
Mednet Member
Mednet Member
Rheumatology · Uniformed Services University of the Health Sciences (USUHS)

Hydroxychloroquine has an initial whole-blood half-life of around 5 days, while its terminal half-life is around 40 days (Costedeau-Chalumeau et al., PMID 27745934). The former is relevant to evaluating whole blood levels after a dose change.

This was confirmed in the PLUS study (see figure 2 in Cost...

Register or Sign In to see full answer