What is the appropriate time interval to assess treatment response in primary vaginal SCC?
Would you delay salvage surgery for a stage I primary vaginal cancer with partial response but no new disease at 3 months after radiation (EBRT + brachytherapy boost) alone?
If this approach is accepted in HPV-mediated H&N and anal cancer, does the same principle apply for gynecologic SCC?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
I would favor biopsy before any intervention. If positive, would need surgical salvage (similar principle as cervical cancer).
This review gives some biological differences between cervical and other HPV-associated malignancies.
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