What is the best dose to treat splenomegaly with pancytonenia in the setting of myelofibrosis?
Would you use 10 Gy in 1 Gy per fraction as mentioned in a litterature review in Pubmed?
Answer from: Radiation Oncologist at Academic Institution
I have treated occassionally and have recommended 20 cGy to 25 cGy alternate day x 3 or 4 fractions
It works well as spleen is a very radiosensitive organ and does not require doses above 150 cGy
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