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What is the best dose to treat splenomegaly with pancytonenia in the setting of myelofibrosis?

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Mednet Member
Mednet Member
Radiation Oncology · Weill Cornell Medical College

I have treated occassionally and have recommended 20 cGy to 25 cGy alternate day x 3 or 4 fractions

It works well as spleen is a very radiosensitive organ and does not require doses above 150 cGy

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