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What is the best way to approach elevated liver enzymes in patients treated with combination TKI and immunotherapy?

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Mednet Member
Mednet Member
Medical Oncology · Johns Hopkins Medicine

We rely on clinical judgment in this case as both TKIs and immunotherapies can cause elevation of liver enzymes. Currently, the recommendations in case the attribution of the hepatitis is questionable is to hold both drugs and to check the liver enzymes daily; if it improves, then it is likely due t...

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What is the best way to approach elevated liver enzymes in patients treated with combination TKI and immunotherapy? | Mednet