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What is the drug of choice in order of preference for neuropathy associated with different agents used for breast cancer treatment?

In addition to gabapentin and Lyrica, what else can you do for chemotherapy induced neuropathy?
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What is your first line treatment for neuropathy associated with different agents used for breast cancer treatment?

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3 Answers
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Medical Oncology · Columbia University Medical Center
Answered on

Unfortunately, many of the large trials have not identified a strategy that is effective for CIPN. It is important to tell patients to avoid some supplements. Studies have shown that acetyl-l-carnitine can make the symptoms worse. There is some evidence that exercise may result in decreased symptoms...

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Radiation Oncology · Henry Ford Health System
Answered on

There are not many studies looking at treatment for CIPN. Usually our med onc start the patients on Vitamin B6 and if that is not effective Gabapentin. I also recommend acupuncture for patients which seems to be effective especially in patients not responding to Gabapentin. However, it does take 12-...

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Medical Oncology · NYU Perlmutter Cancer Center
Answered on

The best way to approach it is with prevention and we found cryotherapy to be very effective and inexpensive method of prevention. Unfortunately, it is not applicable for oxaliplatin.

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