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What is the likelihood of recovery of the hypothalamic-pituitary-adrenal (HPA) axis in patients who develop immunotherapy induced adrenal insufficiency?

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Endocrinology · Johns Hopkins Endocrinology and Pituitary Center

Essentially zero. ICI-induced central adrenal insufficiency is almost always permanent.

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What is the likelihood of recovery of the hypothalamic-pituitary-adrenal (HPA) axis in patients who develop immunotherapy induced adrenal insufficiency? | Mednet