What is the longest acceptable interval between radical orchiectomy and adjuvant BEP for Stage IIB/III pure seminoma in the age of COVID-19?
Drs. @Dr. First Last and @Dr. First Last have worked with GCT experts to create practical recommendations during this pandemic. You can read these here.
Briefly, these patients should be still be treated with timely curative intent. Treatment decisions will need to be individualized for each patient and chemo may need to be postponed until symptoms have regressed. Full recommendations from Drs. Nichols, Housri et al. pertaining to your question listed below:
In patients without SARS-CoV-2 and COVID-19, BEP x 3 in IGCCC good risk is preferred unless there is an ironclad contra-indication to bleomycin. In patients with concurrent good risk disease and COVID-19, there are no data and the majority of our group would recommend that proceeding wi...
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So I assume this isn't adjuvant therapy if this is stage IIA/B seminoma. If it is a 2-2.5 cm node and marker negative, our current approach is to repeat the CT in 6 weeks and if it is growing, initiate BEP X 3 as an outpatient. In the interim, I would emphasize very heavily the SAR-CoV-2 precautions that all patients and all people should be taking.
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