What is the minimum eGFR at which we should avoid initiating SGLT2i therapy?

The minimum eGFR to avoid initiating SGLT2i is different depending on the medication.

Canagliflozin or Invokana is less than 30 ml/min.

Dapagliflozin or Farxiga is less than 25 ml/min.

Empagliflozin or Jardiance is less than 20 ml/min.

With recent study suggests you still can continue the therapy with Empagliflozin even after the patient who is already on Empagliflozin starts dialysis.