What is the optimal approach to treat isolated diastolic hypertension?

Isolated diastolic hypertension occurs less commonly in the adult population, where the majority of the outcome trials in hypertension have been conducted. Much of the treatment of hypertension in younger patients is extrapolated from these trials. In my practice, I look more closely for secondary causes like aortic coarctation, renal genetic disorders, and endocrine disorders that lead to excess cortisol. I may utilize 24-hour ABPM in the evaluation. If it is just primary hypertension in a youn...