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What is the optimal choice of therapy for a patient with Hodgkin variant of Richter's transformation from underlying CLL/SLL?

Does age influence your choice of regimen?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Hematology · UMass Chan Medical School
Answered on

I treat it similar to denovo Hodgkins Lymphoma with Brentuximab AVD for high risk versus ABVD for standard risk. If EBER-positive lymphoma, then there is a role for rituximab use in addition to chemo. Gupta et al., PMID 35291669

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