What is the optimal interval between vaginal cuff brachytherapy sessions?
At our institution we often give 5.5 Gy x 4 fractions. There really does not appear to be a general consensus regarding timing. Interested in what other providers do as far as treatment sequence, i.e. only two factions per week or three per week (separated by 48 hour's).
Answer from: Radiation Oncologist at Academic Institution
At UAB, we gave 7 Gy x 3 = 21 Gy at 0.5 cm at the depth, treating every other day but we can vary somewhat the treatment interval according to patient transportation.
Answer from: Radiation Oncologist at Academic Institution
PORTEC-2 did 7 Gy x 3 to 0.5cm depth once per week, which is the approach I use for anyone receiving that fractionation scheme, including patients receiving cuff + chemo.If q3 week CarboTaxol is involved, I shuffle the schedule slightly with the goal of completing VCB between cycles of chemo, but my...
Answer from: Radiation Oncologist at Community Practice
The standard at my current institution follows the PORTEC-2 regimen, delivering 7 Gy x 3 to 0.5 cm depth once weekly. However, I am planning to change our standard to twice weekly. Where I trained, we typically did 5.5 Gy x 4 to 0.5 cm depth twice weekly. Per the ABS Guidelines (Small Jr et al....
Comments
Radiation Oncologist at Mallory Radiotherapy, PLLC
I use the same 3 fraction regimen and deliver it e...
I use the same 3 fraction regimen and deliver it e...
Radiation Oncologist at Vanderbilt-Ingram Cancer Center
Interesting as to that specific recommendation fro...
Interesting as to that specific recommendation fro...
Answer from: Radiation Oncologist at Community Practice
For 10 years, I have been doing VCB at 700 cGy x 3 to 5 mm primarily and at 400 cGy x 3 to 5 mm as a boost on a Tuesday–Friday–Tuesday schedule (3 fractions over 1 week). It has been very well-tolerated and I am not aware of any recurrences at the cuff.
Just to confirm, you have seen no toxicity issues ...