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What is the optimal sequencing of systemic therapy and consolidative thoracic RT for oligometastatic NSCLC?

Do you favor systemic therapy for X cycles followed by restaging and then consolidative radiation (SBRT or CRT)? Or do you prefer up front thoracic directed therapy?
1 Answer
Mednet Member
Mednet Member
Radiation Oncology · University of Colorado School of Medicine
Answered on

I personally prefer doing sequential therapy first, for 3-4 months, then reassess for continuing oligometastatic state. This is how it was done in the Gomez randomized phase II study in which a PFS and OS benefit was observed. I think that by doing systemic therapy first some patients who are rapidl...

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